Indomethacin

Indomethacin is a prescription medication that belongs to a group of drugs called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). It is primarily used to reduce pain, inflammation, and swelling caused by conditions like arthritis, gout, and tendonitis.

Uses of Indomethacin

• Arthritis: Indomethacin is often prescribed to relieve joint pain, stiffness, and swelling in people with osteoarthritis or rheumatoid arthritis.

• Gout: It is effective in relieving the sudden, intense pain and inflammation that comes with gout attacks.

• Other Conditions: It can also be used to treat other painful conditions, like bursitis and tendonitis.

How Indomethacin Works

Indomethacin works by blocking certain natural chemicals in the body that cause inflammation and pain. These chemicals, called prostaglandins, are responsible for pain, swelling, and redness in inflamed areas. By reducing prostaglandins, Indomethacin helps ease symptoms like pain and swelling.

How to Take Indomethacin

• Forms Available: Indomethacin usually comes as capsules, extended-release capsules, and a liquid suspension.

• Dosage: The dosage varies depending on the condition. It’s essential to follow your doctor’s instructions about how much to take and when.

• With Food: Take Indomethacin with food or milk to help reduce the risk of stomach upset.

Possible Side Effects

While many people tolerate Indomethacin well, it can cause some side effects. Here’s what to look out for:

• Common Side Effects:

• Upset stomach, nausea, or vomiting

• Dizziness or headache

• Heartburn or stomach pain

• Serious Side Effects: Although rare, some people may experience:

• Severe stomach pain or signs of bleeding (such as black or bloody stools)

• Chest pain, shortness of breath, or unexplained swelling

• Signs of an allergic reaction, like a rash, itching, or difficulty breathing

If you notice any serious side effects, stop taking Indomethacin and seek medical help immediately.

Precautions

• Allergies: Avoid Indomethacin if you are allergic to NSAIDs like ibuprofen or aspirin.

• Medical History: Inform your doctor if you have any history of stomach ulcers, heart disease, liver or kidney problems.

• Pregnancy and Breastfeeding: Indomethacin may not be safe to take during pregnancy or breastfeeding. Consult your doctor if you are in either situation.

Interactions with Other Medications

Indomethacin can interact with several other medications, such as:

• Blood thinners (e.g., warfarin) which may increase bleeding risk

• Blood pressure medications which might be less effective

• Other NSAIDs, which can increase the risk of side effects

Always let your doctor know about any medications or supplements you are taking.